You can make this change by editing the Registry. (As always, be sure to back up your Registry files--system.dat and user.dat--first.) To open the Registry Editor, click the Start button, select Run, type
regedit
and click OK.
Navigate your way to HKEY_CURRENT_USER/Software/Microsoft/Windows/CurrentVersion/Explorer/RunMRU, and in the right pane, you'll see all the items that currently appear in your Run list. To delete an item, right-mouse-click its letter under Name, then select Delete. Click Yes to confirm, and the item disappears. Repeat these same steps for the rest of the items you want to delete (you can select more than one at a time by holding down Ctrl as you click each item), being sure not to delete the items named MRUList and (Default). Close the Registry Editor, restart the computer, check out your Run list, and you'll find that it's clean as a whistle!